[Abstract] Purpose To explore the decision-making characteristics of deviant personality college students. Method A total of 55 deviant personality students and 31 healthy control students were enrolled. The Iowa Gambling Task (IGT) was conducted and the Personality Inventory for DSM-5 (PID-5) was adminstered. Result Two groups dropped off card A’s chooses（F=18.17,p<0.01）and increased card D’s chooses（F=12.93,p<0.01）gradually. The index (A+B)-(C+D) of two groups decreased significantly during the IGT test（F=9.25,p0.01).The deviant personality group showed significantly higher ratio of A/(A+B) than the control group. (t=-2.24,p=0.03). The index (A+B)-(C+D) of two groups decreased significantly during the IGT test(F=9.25,p0.01).There was a significant correlation(p<0.01,r=0.38) between antagonism dimension and (A+B)-(C+D);The six traits belonging to antagonism had significant correlation with (A+B)-(C+D): hostility (r=0.25,p=0.02), manipulativeness (r=0.25,p=0.02), deceitfulness (r=0.25,p=0.02), grandiosity (r=0.36,p<0.01), attention seeking (r=0.32,p<0.01), callousness (r=0.26,p=0.02). Conclusion The deviant personality people tend to taking risky strategy in decision-making, and the decision-making.strategy may be associated with personality trait Antagonism dimension.