Objective：To investigate the influence factors for the hospitalization costs of Parkinson’s disease (PD). Methods：The 320 patients with PD at the First Affiliated Hospital of Nanjing Medical University were recruited from January 2009 to December 2015. Thirty-seven patients accepted deep brain stimulation (DBS) operation and 283 received other medical treatment. Patients were categorized to five stages according to Holehn Yahr (H Y) standard. The hospitalization costs were compared along with different stage of PD, length of hospitalization and concurrent infection. Results：Among the nonoperative patients with PD, there was a significant linear correlation between the hospitalization costs and length of stay (r=0.685,P<0.001).The age, sex, concurrent infection and different stage were significantly correlated with the hospitalization costs as well (P<0.05). The sex, concurrent infection and stage were also significantly correlated with the average hospitalization costs. And the age, hospitalization year, concurrent infection and stage were significantly correlated with the length of stay. The rate of concurrent pulmonary infection was positively correlated with patient’s stage patients (χ₂= 10.47,P =0.005). The hospitalization costs were significantly higher in the operation group than that of non-operative group (t=7.74,P <0.001). Conclusion：The hospitalization costs and length of stay of the nonoperative PD patients relate to the baseline characteristics including age, gender, concurrent infection and patient’s stage.