Teacher-student relationship is one of the most basic interpersonal relations in colleges and universities. Good teacher-student relationship is very important for the quality of teaching and the healthy development of students. This article will analyze the current situation of teacher-student relationship in colleges and universities and have a in-depth thinking about the problems existed in it. At the same time, this article will try to put forward helpful measures to construct harmonious teacher-student relationship, achieve teaching objectives and cultivate high quality talents for our society.