Objective：The relationship between clinic doctor-patient interaction and patient satisfaction was analyzed to put forward reasonable suggestions to improve the quality of doctor-patient interaction and patient satisfaction. Methods: Doctor-patient language were quantified by RIAS which was widely used abroad, the relationship between language and satisfaction was analyzed combining with questionnaire survey on patient's satisfaction with consultation. Results: More doctor’s biomedical information gathering, patient’s information search degree, psychosocial Information giving, and positive conversation are associated with higher patient’s satisfaction, while doctor’s negative conversation and patient’s age are associated with lower patient’s satisfaction. Conclusion: Doctors should pay more attention to psychosocial factors while attach importance to patient's diseases, avoid negative language, and focus on the needs of elderly patients. Meanwhile, governments or hospitals at all levels should strengthen the popularization of disease and health knowledge among patients, which can enhance patient satisfaction.