高血压个体家庭连续自测收缩压特征描述与分析
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安徽医科大学卫生管理学院

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国家自然科学基金项目(面上项目,重点项目,重大项目)


Self-measured sequential systolic blood pressure: characteristics and implications for personalized case management
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School of Health Administration, Anhui Medical University

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    摘要:

    目的:从个体角度出发,分析患者自测收缩压和血压测量行为特征,为传统的以群体为对象的研究提供补充,为高血压个性化精准干预提供线索。方法:从科大讯飞医疗高血压管理平台下载选定患者的全部收缩压自测数据及测量日期和时间。通过安徽省气象局官方网站查阅并过录患者血压自测时的日平均气温。将两种来源数据合并后导入微软excel表格,利用其中的插图功能为每位患者绘制四种散点图。分类逐一人工观察上述过程绘制的全部散点图,从每类散点图中挑选4个差别明显的个例(共16个)以构成易于直观比较的散点图组合。结果:每种类型的“组合图”均可见差别炯异的散点图。有的呈上升趋势,有的呈下降趋势,有的相对平稳,有的呈周期波动,有的分布范围明显宽于另一些,有的则可见明显的散点密集区、稀疏区和空白区。结论:个体间的收缩压表现差异悬殊,测量行为也各有特点,传统的主要关注群体血压集中趋势的做法忽视了个体差异,分析个体的单独表现有可能为高血压个性化精准管理提供新的线索。

    Abstract:

    Objective: The study aims at identifying useful characteristics with self-measured individual systolic blood pressure (SBP) and informing personalized hypertension case management. Method: Firstly, the study downloaded blood pressure measurements from the online database maintained by iFLYTEK and ambivalent temperature from the official website of Anhui Provincial Meteorological Bureau. Then the study used the graphics function of WPS spread sheet in making four types of scatter plots. Finally, the study performed manual examination of all scatter plots and picked up 4 typical plots for each of the four types of plots. Each of these plots represents the SBP features of one of the 16 individual hypertension patients coded as P1 through to P16. Result: Each of the four types of scatter plots picked up above presents distinguished patterns. Some of the plots present an increasing trend; while others, relatively stable, fluctuating and decreasing trend. Some plots display apparently greater range of variations than others. Some plots show vertical blank zones; while other, horizontal or no blank zones. Conclusion: Great variations exist between individual hypertension patients and traditional way of estimating aggregate patterns or trends often masks these differences. The current study should inform future personalized hypertension case management.

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  • 收稿日期:2019-07-12
  • 最后修改日期:2019-12-09
  • 录用日期:2020-05-04
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