This study aims to provide theoretical basis for training a high-quality team of nurses by discussing the management experience of head nurses in newly built hospitals. Methods:Qualitative research and semi-structured interview were used to interview14 head nurses on their management experience in new hospitals. Research data was collected and analyzed, and theme was concise. Results: The resulting themes included opportunity, challenge, and vision. New hospitals offered head nurses promotion opportunities and improved their abilities in allSaspects. However, special environment of new hospitals also made it difficult for head nurses to face such challenges as scientific research, communication, coordination, and teaching. Head nurses hoped to get enough support from hospitals to improve management level and performance. Conclusion: Though head nurses in newly built hospitals had short working time and relatively insufficient management experience, they were full of enthusiasm for work and had a strong desire to improve themselves. Hospitals should adopt various ways to meet their needs for self-improvement.