In view of the shortcomings of the existing traditional teaching mode of stomatology graduate students, the SPOC-based flipped classroom combined with the PBL teaching mode is used to design a teaching model which is suitable for the characteristics of stomatology graduate students, and to train students the ability to use theoretical knowledge analysis effectively and solve clinical issues autonomously, the ability to transform theory into clinical business skills quickly, so as to make full use of teaching resources. The advantages of flipped classroom teaching mode based on SPOC, such as flexible allocation of learning time and full mobilization of learning enthusiasm, are combined with the advantages of PBL learning mode, which emphasizes students" cooperation, communication and mutual learning to achieve the effect of "1 + 1> 2" and finally form a new teaching mode suitable for the characteristics of clinical skills training of stomatology graduate students.