Nowdays we have entered the era of cloud computing and big data. The 5G mobile communication technology provides a lot of possibilities for re-improving the level of informatization applications in all walks of life. At the same time, 5G has a strong integration effect with a variety of advanced information and communication technologies, forming a 5G+ technology ecosystem. In this paper, the development of digital medicine under 5G+ environment is analyzed, the influence of 5G+ on the development of digital medicine is discussed, two key problems existing in digital medicine and corresponding solutions are proposed, and finally the future of digital medicine is looked forward to.