Purpose: To understand the current status, hotspots and trends of international medical quality and safety research, and to provide references for promoting related research; Method: Retrieve the research papers published in "BMJ Quality & Safety" and use bibliometrics and graph theory of scientific knowledge to perform statistics and analysis on the papers; Results: A total of 889 papers were included, with 66 to 159 papers published each year; the United States is the country with the most papers published, the Harvard University is the institution with the most papers published, and Charles Vincent is the author with the most papers published. The citation rate of the paper is 97.2%, the average number of citations is 21.45, the H-index is 59, and the cited literature is 14,192; a total of 31 keywords appear The frequency exceeds 30 times, of which "health care" appears the most; Conclusion: Many high-level research institutions and core author groups to lead the development of related research; teamwork, adverse drug events, and patients the center's care, clinical practice guidelines, etc are hot research topics; Nursing technology and services have attracted much attention to the guarantee of medical quality and safety; strengthening the application of information technology and carrying out evidence-based research to reduce diagnosis errors are important research frontiers and trends..