The establishment and development of our country’s health and epidemic prevention system have distinct characteristics of the times. Under the leadership of the Communist Party of China, health and epidemic prevention have gone through the start of the revolutionary base, the development of socialist construction, the maturity after reform and opening up, and the innovation of the new era, and gradually formed a complete 的系统。 The system. The sanitation and epidemic prevention system is directly related to the lives and health of the people. To achieve the goal of a healthy China, the party and the government attach great importance to the development of the sanitation and epidemic prevention system. Interpreting my country's 100-year history of health and epidemic prevention is beneficial to summing up experience from history and improving the country's ability to deal with major risks and challenges. This article starts with the development process of the health and epidemic prevention system, combs the development of the health and epidemic prevention system since the new democracy, summarizes the development experience of each period, and provides reference for the innovative development of my country's health and epidemic prevention system in the new era.