With the development of network and digital technology, big data analysis has become a new and powerful tool in clinical research and teaching. From the perspective of medical literature and data-driven analysis, this study proposed a new clinical teaching mode, in which related medical resources were comprehensively gathered and classified, each key knowledge point was labeled and associated. Through this technology, teachers can keep pace with the ever expanding frontier of the specific topic, set the realm of discussion and guide students when the discussion went off the track. This idea will reconstruct the framework of clinical seminar, set free the ability of students and keep the seminar efficient and coherent.