Interpersonal health communication has significant effect on campaign-targeted health outcomes, which rely on individuals’ elaboration and reflection of that information of health campaign through social network. Based on international studies on the relationship between interpersonal health communication and health campaign, this paper adopt Mapping Knowledge domain to outline the current situation from three aspects: timescales, nation distribution and the topic of health campaign. The paper further established a research framework from four aspects: the theory of interpersonal communication, types of communication behavior, factors that influence interpersonal health communication and the effect of interpersonal communication on campaign-targeted health outcomes using content analysis. Given the findings that fruitful research has obtained on the intersection between interpersonal health communication and health campaign, it deserves further research on the systematic influence of interpersonal communication in the context of health campaign and applying it on health campaign practices in China.