Taking 654 migrant elderly people as the survey objects, this paper explores the effect of different intergenerational support levels on the life satisfaction of migrant elderly people and the sequential mediating effect of self-efficacy and psychological resilience through a questionnaire survey. The results showed that the four factors of intergenerational support, life satisfaction, self-efficacy and psychological resilience were significantly correlated with each other. Self-efficacy and psychological resilience had a mediating effect between intergenerational support and life satisfaction, with a mediating effect value of 0.198 for self-efficacy and 0.078 for psychological resilience. Self-efficacy and psychological resilience had a serial mediating effect between intergenerational support and life satisfaction.