As a way to resolve the risk of epidemic prevention and control, risk exchange has played an important role in dealing with the problems of information alienation and difficult decision-making in the process of epidemic prevention and control. Covid-19 has formed a certain risk exchange experience and practice in the new crown pneumonia prevention and control. Of course, in the current epidemic prevention and control, there are still some problems, such as legal defects, fragmentation of risk exchange, asymmetry of risk exchange rights, excessive exchange of alienated risk information by new media, lack of corresponding supporting mechanisms and so on. Therefore, it can be constructed from the aspects of repairing laws and regulations, improving the capacity-building of the main team, balancing the rights and obligations of each main body, improving the implementation procedures of risk exchange for epidemic prevention and control, optimizing the relief system and so on.