At present, socialism with Chinese characteristics has entered a new era, and the 20 Spirit has become the program of action and spiritual guidance at the present stage. Contemporary college students, as the main force of building a modern socialist country, shoulder the historical responsibility of realizing the great rejuvenation of the Chinese nation. Therefore, to integrate the twenty spirit into the ideal and faith education of college students is related to the cultivation goal of moral education, the growth and success of college students in the new era, and the fundamental task of building a great modern socialist country. Under the guidance of the Twenty Great Spirits, we will deeply explore the new connotation of the education of ideals and beliefs in the Twenty Great Spirits, integrate the spiritual lineage of Chinese Communists, the "Four self-confidence", the core socialist values, and the mission and task of promoting the great rejuvenation of the Chinese nation through Chinese-style modernization into the twenty great Spirits, and expand the channels of education of ideals and beliefs. In accordance with the idea of adapting to local conditions, starting from the construction of teachers, ideological and political courses in colleges and universities, the second classroom and social practice, the paper innovates a new path of integrating the twenty great spirits into the ideal and faith education of college students.