To establish a collaborative governance framework for the integrated development of multi-campus women's and children's healthcare institutions, this study takes the Anhui Provincial Women's and Children's Medical Center as its empirical research subject. Based on collaborative governance theory, the SFIC model is employed to analyze the current status and challenges of multi-campus integrated development from four dimensions: initial conditions, catalytic leadership, institutional design, and collaborative processes. By integrating the six elements of “human, machine, material, method, environment, and measurement,” the study explores pathways for the integrated development of multi-campus institutions. The study found that multi-campus development faces challenges such as complex initial conditions, insufficient catalytic leadership, institutional design flaws, and stalled collaborative processes. By optimizing physical space layout, improving integrated management models, and unifying the management of the six elements of “human, machine, material, method, environment, and measurement,” the study achieved multi-campus collaborative development, enhanced management efficiency, and strengthened specialized capabilities. The collaborative governance mechanism based on the SFIC model can systematically address the challenges of fragmented resources across multiple campuses, effectively promote strategic planning and resource integration across multiple campuses, and drive the integrated development of multiple campuses.