The amendment to the Law on the Prevention and Control of Infectious Diseases in 2025 is a crucial measure to fully implement the guiding principles of comprehensively strengthening and improving the development of laws and regulations in the field of public health. As the number of criminal cases involving infectious diseases has been rising year by year, the proactive involvement of procuratorates in the investigation phase of such cases in the criminal justice field is a response to the "timeliness" requirement for infectious disease prevention and control, and also an inherent part of advancing the modernization of the national emergency management system and governance.Currently, procuratorates face difficulties in their proactive involvement in criminal cases involving infectious diseases, such as unclear involvement mechanisms, insufficient technical response capabilities, and abnormal delays in procedural progress. To address these issues, it is necessary to strengthen legislative safeguards and clarify the specific standards for procuratorates' proactive involvement in such cases. Meanwhile, efforts should be made to enhance the level of procuratorates' proactive involvement from the dimensions of crime application, evidence review, and coordination between administrative law enforcement and criminal justice.In addition, emphasis should be placed on protecting the right to defense and personal information rights of the prosecuted, so as to promote the transformation of procuratorates' proactive involvement from a "passive response" to an "active governance" approach.