?Seeking empowerment through artificial intelligence (AI) is an inevitable trend in humanistic literacy education for medical students in the digital intelligence era.? This aligns with the historical shift towards intelligent transformation in the medical and pharmaceutical industry, represents a necessary choice for enhancing the targeted cultivation of medical students" humanistic qualities, and meets the practical need for a paradigm shift in this cultivation. ?However, AI also has inherent limitations that are difficult to overcome, such as the scenario recreations it generates ?cannot replace? the bonding through emotional resonance between teachers and students grounded in life-affirming care; the personalized teaching it provides ?cannot eliminate? value biases and ethical risks; the technical assistance it offers ?cannot fundamentally stimulate? medical students" intrinsic motivation to learn; and the superficial evaluation metrics it relies on ?cannot fully reflect? the quality of cultivation.? Therefore, we must ??strengthen teacher-student emotional interaction?, integrating technological advantages with humanistic care; ?establish human-machine collaboration mechanisms?, emphasizing value guidance and ethical norms; ?reconstruct the core of education?, igniting medical students" intrinsic learning motivation; optimize the evaluation system?, promoting multidimensional dynamic assessment, the ultimate goal is to achieve the unification of teacher guidance and AI assistance.