This paper introduces the perspective of "embodiment" theory to re-examine Professor Hong Shilu's research practices during the founding period of modern parasitology in China. Hong's outstanding contribution lies not in the mere application of Western parasitological knowledge but in pioneering an "embodied science" paradigm—through personally immersing himself in epidemic areas, improving techniques with his own hands, establishing organizations, and imparting scientific knowledge firsthand. This paradigm emphasizes: scientific cognition stems from scientists' direct sensory experiences gained through bodily embeddedness in epidemic sites; technological innovation involves creative adaptation by scientists' hands under local resource constraints; organizational building reflects institutionalized efforts to root research subjects in local social networks; and knowledge dissemination constitutes a cultural process of integrating scientific concepts into the daily bodily habits of the public. Through an in-depth analysis of Hong's "embodied practices" in combating diseases such as paragonimiasis and hookworm, aimed at revealing a profound and dynamic mechanism in the "localization" process of modern Chinese science, offering critical intellectual resources for rethinking the practical essence of science and advancing contemporary technological self-reliance.