Based on policy documents, legal provisions and institutional frameworks relating to chronic diseases in the Yangtze River Delta region from 2000 to 2023 , this study systematically analysed trends in the scope of attention paid to chronic diseases in Shanghai, Zhejiang, Jiangsu and Anhui, as well as differences between the four regions, and explored the correlation between the scope of attention and the effectiveness of chronic disease prevention and control. The results show that the scope of attention to chronic diseases in Shanghai increased from 22.7% to 68.2%,whilst in Zhejiang it rose from 4.5% to 63.6% . In Jiangsu and Anhui, the scope increased from zero to 54.5% and 59.1% respectively.Correlation analysis indicated that the scope of focus on chronic diseases in all four regions was significantly positively correlated with prevention and control outcomes(Shanghai: r=0.894,P<0.01;Zhejiang: r=0.901,P<0.01; Jiangsu r=0.761,P<0.01;Anhui r=0.507,P<0.05).The study indicates that Shanghai has the highest scope of focus in the field of chronic diseases, and that the scope of focus in all four regions has increased significantly, confirming the feasibility of using the scope of focus on issues as a quantitative evaluation indicator.