脑机接口临床应用的医学人文审视:基于神经外科临床实践的思考
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东南大学附属中大医院神经外科

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南京市医学科技发展项目(Zkx22041),南京江北新区重点研发计划(ZDYF202514),高水平医院平台建设(科研)-神经外科(CZXM-GSP-KY-202410),东南大学引进学科带头人启动金(CZXM-GSP-RC152),江苏省自然科学基金项目(BK20230221),中国博士后面上项目(2023M731766),江苏省卫生健康委医学科研项目(M2022092)


A Medical Humanities Perspective on the Clinical Application of Brain–Computer Interfaces: Reflection on Neurosurgical Practice
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Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing

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    摘要:

    脑机接口(brain-computer interface,BCI)正在由实验室验证逐步进入临床转化阶段,与一般医疗器械不同,脑机接口直接连接神经活动与外部设备,其临床价值不仅取决于信号采集、解码精度和功能输出,更取决于患者能否获得具有持续性、可负担且符合生活目标的临床获益。本文立足神经外科临床实践,围绕BCI在运动功能、交流沟通及神经康复等领域的临床应用进展,分析长期安全性、适应证选择、术后康复与随访、疗效评价及多学科协作等现实困境,进而讨论知情同意、人格同一性与神经自主性、神经数据隐私、责任归属和公平可及等方面的伦理与社会挑战。文章提出,应将脑机接口的临床评价从技术是否可行转向患者重视的临床获益,以持续性知情同意、全周期风险评估、患者报告结局为导向的疗效评价、多学科长期随访和全过程伦理评估为支撑。对于神经外科医生而言,真正重要的并非仅仅完成一次手术植入,而是在每一个关键决策节点回答这项技术究竟为眼前这位患者带来了什么。

    Abstract:

    Brain-computer interface (BCI) is gradually entering the clinical transformation stage from laboratory verification. Different from general medical devices, BCI is directly connected to neural activity and external devices. Its clinical value depends not only on signal acquisition, decoding accuracy and functional output, but also on whether patients can obtain clinical benefits that are sustainable, affordable and in line with life goals. Based on the clinical practice of neurosurgery, this paper focuses on the clinical application progress of BCI in the fields of motor function, communication and neurorehabilitation, analyzes the practical difficulties such as long-term safety, indication selection, postoperative rehabilitation and follow-up, efficacy evaluation and multidisciplinary collaboration, and then discusses the ethical and social challenges of informed consent, personality identity and neuroautonomy, neurodata privacy, responsibility attribution and fair access. This paper proposes that the clinical evaluation of brain-computer interface should be shifted from the technical feasibility to the clinical benefits that patients attach importance to, supported by continuous informed consent, full-cycle risk assessment, patient-reported outcome-oriented efficacy evaluation, multidisciplinary long-term follow-up and whole-process ethical evaluation. For neurosurgeons, what is really important is not just to complete a surgical implantation, but to answer at each key decision-making node what this technology has brought to the patient.

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  • 收稿日期:2026-08-15
  • 最后修改日期:2026-09-08
  • 录用日期:2026-09-11
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