Objective: To investigate the positive role which played by the intraoperative music therapy that combined with psychological intervention to reduce psychological stress,relief the surgical pain and cut down the body’s stress station. Methods: Sixty cases of selective cesarean section were randomly divided into two groups:the cases of control group were received routine observation and nursing care,the intervention group cases were provided psychological care interventions and intraoperative music therapy besides the measures of the control group. Anxiety scores(SAS),the divergence of plasma cortisol(Cort),glucose(Glu),blood pressure,heart rate,pain scores(VAS)levels were observed before and after the intervention. Results: SAS(self anxiety scores)in both groups were no significant differences before the intervention and the intervention group reduced anxiety,lower than the control group(P < 0.05). In the level of Cort,Glu and VAS,the intervention group was more positive than the control group(P < 0.05). Heart rate,blood pressure and Apgar score showed no significant difference between the two groups. Conclusion: The intraoperative music therapy combined with psychological intervention can relieve stress in patients with cesarean section.