To constructing the medical humanities, which is to make medical science possesses humanization, from the logical starting point of humanism as well as the philosophical perspective and the human spirit to analyze the intrinsic link between subject and object in medical activities, between public welfare and profitability, as well as between humanities and medical science. We explore the major problems in the current construction of medical humanities from the cultural roots, which embody that the ultimate medical concern on patients’ life is the humanistic care to patients.