Objective： To explore the decision?making characteristics of college students with deviant personality. Methods: A total of 55 students with deviant personality and 31 healthy control students were enrolled. The Iowa Gambling Task（IGT） was conducted and the Personality Inventory for DSM-5（PID-5） was administered to compare the decision?making and PID-5 results between the two groups. Results: Two groups dropped off card A’s chooses（F=18.17, P<0.01） and increased card D’s chooses（F=12.93, P<0.01） gradually. The indexes of（A+B）-（C+D） of two groups were decreased significantly during the IGT test（F=9.25, P<0.01）. The deviant personality group showed significantly higher ratio of A/（A+B） than the control group（t=-2.24, P=0.03）. There were no significant differences of indexes of（A+B）-（C+D） between two groups（t=-0.61, P=0.55）. There was a significant correlation（r=0.38, P<0.01） between antagonism dimension and（A+B）-（C+D）; The six traits belonging to antagonism had significant correlation with（A+B）-（C+D）: hostility（r=0.25, P=0.02）, manipulativeness（r=0.25,P=0.02）, deceitfulness（r=0.25, P=0.02）, grandiosity（r=0.36, P<0.01）,attention seeking （r=0.32, P<0.01）, callousness（r=0.26, P=0.02）. Conclusion: The deviant personality people tend to taking risky strategy in decision?making, and the decision?making strategy may be associated with personality trait antagonism dimension.