To construct the performance evaluation framework for clinical department heads of China’s public hospitals， and provide theoretical basis and technical support for the modern hospital management. Literature reviewing， Delphi method and analytic hierarchy process were used to develop the framework. The validity and reliability of the index system were validated by the comprehensive scoring method， weighted TOPSIS method and weighted rank?sum ratio (RSR) method. We created the performance evaluation system consisted 4 class-1 indicators， 13 class-2 indicators and 66 class-3 indicators. This index system had better reliability and validity. Spearman test verified that the 3 evaluation methods were significantly related. Scientific studies can help us to build a scientific and practical work performance assessment indicator system for clinical department heads of China’s public hospitals.