A total of 50 tertiary hospitals in Jiangsu Province were investigated by convenient sampling and snowball sampling. The number of hospitals that established the professional team for antimicrobial stewardship in 2011 was the largest; 52% of hospitals allocated special funds to support antimicrobial stewardship activities; Only 52% of hospitals regularly gave feedback on antimicrobial use and communicated to physicians; 46% of hospitals did not conduct pre?audit and feedback on antimicrobial prescriptions in the outpatient department, and 22% in wards; 84% of computer systems used antimicrobial stewardship?related software; The administrative interventions were widely used. We should improve the multidisciplinary cooperative antimicrobial stewardship (AMS) team, set up special funds for antimicrobial stewardship activities, pay attention to feedback on monitoring information, develop some applications to assist in the management of antimicrobial stewardship, conduct actively pre?audit and feedback, change management ideas, and gradually weaken administrative intervention.