In recent years, public health emergencies occurred frequently, not only causing serious harm to the lives and mental health of the people, but also having a huge impact on social and economic development. How to carry out public health emergency disposal cannot rely solely on the power of the government. Social participation is also essential. Therefore, it is extremely important for social organizations to participate in public health emergency disposal. Through the establishment of the PEST?SWOT model, this study comprehensively analyzed the internal and external environments (strengths, weaknesses, opportunities, and threats) of social organizations participating in public health emergency disposal, and carefully examined the internal and external environments from the four aspects of politics, economy, society, and technology. Development strategies and policy recommendations were put forward for social organizations to better participate in public health emergency disposal. Research findings will provide reference for social organizations to carry out public health emergency disposal in the new era.