Since the founding of the People’s Republic of China, China’s public health diplomacy has experienced four stages: initial creation, reform and adjustment, rapid development and new development, and achieved a great leap from participating in global public health cooperation to leading global public health cooperation. In this evolution process, there are four characteristics: public health diplomacy has always been consistent with the line and policy of the Communist Party of China; the scope of communication has changed from local communication to comprehensive communication; the way of communication has changed from hard communication to soft communication; the diplomatic status has changed from participation to guidance. Taking history as a mirror, the promotion of public health diplomacy in the new era must adhere to the leadership of the Communist Party of China and obey the party’s diplomatic policy, keep pace with the times and improve the level of opening up in the field of public health, adhere to self?centered and master the voice of public health diplomacy, and adhere to independence and innovate the traditional public health governance model.