儿童青少年肥胖病代谢手术应用进展
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R589.2

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江苏省自然科学基金面上项目(BK20201115);中华国际交流基金会森美中华糖尿病科研基金(Z-2017-26-1902)


Progress of metabolic surgery in children and adolescents with obesity
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    摘要:

    我国儿童青少年肥胖患者迅速增加,合并多种肥胖并发症,增加成年后肥胖及相关并发症发病风险,减少预期寿命。目前国内尚无药物批准用于儿童青少年减重治疗,代谢手术是生活方式干预无效的中重度肥胖儿童青少年患者可选用的减重措施。国内外研究显示,此类人群代谢术后,有效减重,改善、逆转2型糖尿病、高脂血症、高血压等肥胖相关并发症,围手术期并发症发生率与成人类似,术后补充和监测营养元素利于减少远期营养不良相关并发症,同时需关注患者的精神心理状态。本文综述国内外儿童青少年代谢手术开展情况、手术适应证、禁忌证、术式及随访要求。

    Abstract:

    Obesity is increasing rapidly among children and adolescents in China,which is associated with multiple obesity complications,the risk of obesity and related complications in adulthood,and reduction of life expectancy. Nowadays,no medication is approved for weight loss in children and adolescents in China. Metabolic surgery has been considered as weight loss treatment for children and adolescents with moderate to severe obesity when lifestyle interventions are ineffective. Studies in China and other countries have shown that children and adolescents with moderate and severe obesity achieved substantial weight loss after metabolic surgery,accompanied with improvement,even reversal of obesity - related complications such as type 2 diabetes,dyslipidemia and hypertension,etc. and similar perioperative complication as adults. Postoperative appropriate nutrient supplement and monitoring are beneficial to reduce the long - term malnutrition complications,and patients’mental health also need to be monitored. This article reviewed the development of metabolic surgery in children and adolescents in China and abroad,and also indications, contraindications,surgical procedures and follow-up requirements.

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韩涛,冯文焕.儿童青少年肥胖病代谢手术应用进展[J].南京医科大学学报(自然科学版),2022,42(10):1482-1487

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  • 在线发布日期: 2022-10-25
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