语音识别技术在孤独症谱系障碍诊断中的研究进展与应用展望
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南京医科大学附属脑科医院院长办公室,江苏 南京 210024

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南京市卫生科技发展专项资金(ZKX24053)


Research progress and application prospects of speech recognition technology in autism spectrum disorder diagnosis
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Office of the Dean,the Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210024 ,China

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    摘要:

    孤独症谱系障碍(autism spectrum disorder,ASD)是一种起病于发育早期的神经发育障碍,其核心症状主要表现在语言和社会交往方面。传统诊断工具(如《自闭症诊断观察量表第2版》)应用广泛,但在低龄儿童和基层医疗中可及性与客观性不足。语音识别技术因其量化能力强、成本较低、识别婴幼儿早期言语异常的灵敏度高,正成为辅助诊断ASD的重要手段。文章系统梳理了语音识别技术在不同年龄段早期筛查、共病情绪问题诊断、疾病严重程度评估及多模态融合等方面的最新研究。结果显示,通过提取基频、语速、停顿等声学特征,可有效区分ASD个体与典型发育儿童,并识别焦虑、抑郁及注意力缺陷多动障碍等共病。多模态融合(如脑影像、生理信号和行为数据)可进一步提升诊断准确率。但数据多样性不足、方言与年龄适用性局限、共病干扰及隐私保护等挑战依然突出。

    Abstract:

    Autism spectrum disorder(ASD)is a neurodevelopmental disorder that typically emerges in early childhood,with core symptoms predominantly manifesting in language and social interaction. Although traditional diagnostic tools,such as the Autism Diagnostic Observation Schedule-2,are widely used,they often have limited accessibility and objectivity in younger children and in primary healthcare settings. Due to its strong quantitative capabilities,relatively low cost,and high sensitivity to early speech anomalies in infants,speech recognition technology has emerged as a promising approach for ASD diagnostic support. This paper systematically reviews the latest research on the application of speech recognition in early screening across different age groups, diagnosis of comorbid emotional issues,assessment of disease severity,and multimodal data integration. The findings indicate that extracting acoustic features(such as fundamental frequency,speech rate,and pauses)can effectively distinguish individuals with ASD from typically developing children,while also identifying comorbidities like anxiety,depression,and attention deficit hyperactivity disorder. Furthermore,multimodal fusion(e.g.,neuroimaging,physiological signals,and behavioral data)can further improve diagnostic accuracy. However,challenges persist,including inadequate data diversity,limitations related to dialect and age applicability,confounding effects of comorbid conditions,and concerns over privacy.

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李进宇,赵太宏.语音识别技术在孤独症谱系障碍诊断中的研究进展与应用展望[J].南京医科大学学报(自然科学版),2025,(4):574-579,587

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  • 收稿日期:2024-11-13
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  • 在线发布日期: 2025-04-08
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