颈动脉血管周围脂肪组织的影像学研究进展
作者:
作者单位:

南京医科大学附属明基医院放射科,江苏 南京 210019

作者简介:

通讯作者:

中图分类号:

R814.42

基金项目:

南京市卫生科技发展专项资金(ZKX24064)


Imaging research advances in carotid artery perivascular adipose tissue
Author:
Affiliation:

Department of Radiology,the Affiliated BenQ Hospital of Nanjing Medical University,Nanjing 210019 ,China

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    颈动脉血管周围脂肪组织(perivascular adipose tissue,PVAT)是一种特殊类型的脂肪组织,其与颈动脉外膜在解剖结构上紧密相连,并具有独特的组织学特征和生理功能特性。与普通脂肪组织不同,PVAT通过内分泌和旁分泌机制释放多种生物活性分子,与邻近的血管壁细胞相互作用,参与调控局部炎症反应和血管稳态。PVAT的炎症状态与颈动脉粥样硬化斑块的形成、进展及易损性密切相关,同时也在脑血管病变的发生发展中发挥重要作用。近年来,随着影像学技术的快速发展,无创评估PVAT的炎症状态成为可能。这些技术的应用为早期识别脑血管疾病高风险患者提供了新的工具,并有望优化脑血管疾病的预防策略和个性化治疗。文章系统综述了颈动脉PVAT的病理生理机制、影像学评估技术的最新进展及其在临床中的应用价值。

    Abstract:

    Perivascular adipose tissue(PVAT)of the carotid artery is a specialized type of adipose tissue closely adjacent to the arterial adventitia,possessing unique anatomical and functional characteristics. Unlike ordinary adipose tissue,PVAT releases a variety of bioactive molecules through endocrine and paracrine mechanisms,interacting with adjacent vascular wall cells and participating in the regulation of local inflammatory responses and vascular homeostasis. The inflammatory status of PVAT is closely associated with the formation,progression,and vulnerability of carotid atherosclerotic plaques,while also playing a critical role in the development and progression of cerebrovascular diseases. In recent years,with the rapid advancement of imaging technologies,non - invasive assessment of PVAT inflammation has become feasible. These techniques provide new tools for early identification of high-risk patients with cerebrovascular diseases and hold promise for optimizing preventive strategies and personalized treatment. This article systematically reviews the pathophysiological mechanisms of carotid PVAT,the latest advances in imaging assessment techniques,and their clinical application value.

    参考文献
    相似文献
    引证文献
引用本文

李雯漪,李澄,周丹.颈动脉血管周围脂肪组织的影像学研究进展[J].南京医科大学学报(自然科学版),2025,45(7):1042-1050

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2025-02-28
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2025-07-10
  • 出版日期:
关闭