[Abstract] Objective:To observe and analyze the factors affecting the survival of elderly patients with coronary heart disease. Methods: Datas of 140 elderly patients with coronary heart disease were collected and patients were followed up for an average of 3.5 years. The influencing factors of major adverse cardiac and cerebral events (MACCE) in patients were investigated, and the predictive value of each influencing factor for MACCE was further analyzed. Results:According to the comparison of clinical datas between MACCE group and non-MACCE group, Cox regression analysis and Kaplan-Meier curve, blood urea nitrogen (BUN), total cholesterol (TC), left atrial diameter (LAD), and cardiac valve calcification(CVC) were associated with the development of MACCE in elderly patients with coronary heart disease. There was no correlation between 25 hydroxyvitamin D level and the occurrence of MACCE.According to the results of receiver operating characteristic (ROC) curve, the combination of BUN, TC, LAD and CVC had the greatest value in predicting MACCE.Conclusion:In this study, BUN, TC, LAD and CVC are found to be important influencing factors for the occurrence of MACCE in elderly patients with coronary heart disease, while there is no correlation between the level of 25 hydroxyvitamin D and the occurrence of MACCE.