【Abstract】Objective： this study aims to investigate the effect of microsurgical resection of intracranial cavernous vascular malformation on the retention of developmental venous malformation.Methods：the clinical data of 41 patients with cavernous malformations who delivered in the neurosurgical department of the First Affiliated Hospital of Nanjing Medical University from January 2016 to May 2021 were analyzed retrospectively. They were devided into DVA protected group（23 cases）and unprotected group（18 cases）. KPS score（1 week after surgery）, cerebral edema volume（1 week after surgery）(cm3), postoperative days in hospital (d) and KPS score（3 months after surgery）were compared between the two groups. The influence of malformed vein retention on the above indicators of postoperative function was further investigated when the lesions were more than 18mm in diameter and 21mm in depth as well as involved functional areas. Results：Total resection were achieved in all lesions. The protected group (23 cases) significantly shortened the postoperative hospital stay (P < 0.05) than the unprotected group. When the lesions were more than 18mm in diameter, there was no significant difference in postoperative functional indicators between the two groups. However, when the lesions were 21mm in depth or involved in functional areas, the protected group could significantly improve the KPS score at 1 week after surgery, reduce the volume of cerebral edema at 1 week after surgery and shorten the length of postoperative hospital stay (P<0.05).Conclusion: In the process of microsurgery for cavernous hemangioma with developmental venous malformation, the preservation of malformed veins can improve the prognosis of patients, especially when the lesion is deep seated or close to the functional area, the preservation of DVA is conducive to postoperative functional recovery and shorten hospital stay.