Objective: To analyze the data of inferior vena cava filter (IVCF) in a single-center, and to analysis the problems during the use of IVCF. Methods: Retrospectively analyze the use of IVCF in our hospital from January 2016 to September 2021. Results: A total of 752 IVCFs were implanted, all of which were retrievable. The indications for IVCF implantation including: deep venous thrombosis (DVT, free thrombosis/large acute thrombosis) in 528 cases (70.2%), DVT with pulmonary embolism (PE) in 126 cases (16.8%), and only symptomatic PE in 98 cases (13.0%). Among the 752 IVCFs, 470 were retrieved, with a retrieve rate of 62.5%, and the average indwelling time was 23 ± 33 days (0~530 days). Patient’s age, implantation years, and IVCF brands had statistically significant differences in the retrieve rate (P<0.05). Among the 282 IVCFs that were not removed, the most common reasons were: advanced tumor (31.3%), indications for IVCF still placement (28.7%), old age (27.8%). Conclusions: There are differences in the indications for IVCF placement in different age groups; the retrieve rate of IVCF is increasing; the low retrieve rate is related to malignant tumors, old age, IVCF brand, indications for still placement, and year. Also, IVCF should be selected reasonably according to indications; the benefits and risks of long-term indwelling IVCF should be carefully evaluated, and the retrieve rate needs to be increased.