肥胖人群袖状胃切除术与食物成瘾的关系
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南京医科大学附属常州市第二人民医院 胃肠外科

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胃肠病学重点实验室(CM20223008);常州市社会发展项目(CE20215039);常州市十四五人才(2022CZLJ017);南京医科大学常州医学中心项目(CZKYCMCB202212 & CZKYCMCM202204)常州市“十四五” 卫生健康高层次拔尖人才(2022CZBJ063)


Relationship between sleeve gastrectomy and food addiction in obese population
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1.Department of Gastrointestinal Surgery,the Second People'2.'3.s Hospital of Changzhou Affiliated to Nanjing Medical University,Changzhou,Jiangsu

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    摘要:

    目的 探究肥胖人群袖状胃切除术与食物成瘾的关系,袖状胃切除术是目前最常见的减重手术类型,然而,关于它对心理结果和饮食行为影响的数据很少,有关腹腔镜下袖状胃切除术前后患者食物成瘾变化与身体质量指数(Body Mass Index,BMI)、多余体质量减少百分比(Percentages of excess weight loss,EWL%)及相关检查检验指标的关系尚不明确。 方法 采用一般资料调查表和耶鲁食物成瘾量表2.0(YFAS 2.0)对2021年9月-2022年3月在笔者所在医院行腹腔镜下袖状胃切除的84例患者资料,运用调查问卷及统计学方法对结果进行分析 结果 术前成瘾组大腿围大于非成瘾组(P <0.05)。术后6月成瘾组BMI、胸围、腰围、上臂围、大腿围明显小于术前(P <0.05),术后糖化血红蛋白(Hemoglobin A1c,HbA1c)、总胆红素(Total bilirubin,TBIL)、谷丙转氨酶(Glutamic pyruvic transaminase,GPT 又称ALT)、谷草转氨酶(Glutamic oxaloacetic transaminase,GOT 又称AST)、γ-谷氨酰转移酶(Gamma-glutamyltransferase, GGT)、总胆汁酸(Total bile acid,TBA)较术前明显改善(P <0.05)。成瘾组术后6月EWL% 低于非成瘾组(P <0.05),总胆红素差(ΔTBIL)大于非成瘾组(P <0.05)。结论 术前肥胖人群大多数存在食物成瘾且行腹腔镜下袖状胃切除术后,食物成瘾得到明显改善,患有食物成瘾患者在术后6月的体重改变小于无成瘾患者。

    Abstract:

    Objective: To explore the relationship between sleeve gastrectomy and food addiction in obese population. Sleeve gastrectomy is by far the most common type of weight loss surgery. However, there is little data on its effects on psychological outcomes and eating behavior. The relationship between changes in food addiction and body mass index (BMI), percentage of excess body mass reduction (EWL%), and related test indicators before and after laparoscopic sleeve gastrectomy remains unclear Methods: The General Information Questionnaire and Yale Food Addiction Scale 2.0 (YFAS 2.0) were used to provide data on 84 patients who underwent laparoscopic sleeve gastrectomy at the author"s hospital from September 2021 to March 2022 and their data on 6 months after Laparoscopic sleeve gastrectomy, including Gender, Age, BMI, Chest circumference, Waist circumference, Hip circumference,Upper arm circumference, Thigh circumference, Waist-to-hip ratio,Total bilirubin (TBIL), glycated hemoglobin ( Hemoglobin A1c, HbA1c), Total cholesterol (TC),Low den- sity lipoprotein cholesterol (LDL-ch), total bile acid (TBA), EWL% (Excess body mass reduction rate), the results were analyzed using questionnaires and statistical methods Results: The preoperative thigh circumference of the addicted group was higher than that of the non-addicted group (P <0.05). BMI, chest circumference, waist circumference, upper arm circumference and thigh circumference of the addiction group were significantly lower than those before surgery 6 months after surgery (P <0.05), and HbA1c, TBIL, ALT, AST, GGT and TBA were significantly improved after surgery (P <0.05). The EWL% of the addiction group was lower than that of the non-addiction group (P <0.05), and the ΔTBIL was higher than that of the non-addiction group (P <0.05).Conclusions: Most obese people have food addiction, and after laparoscopic sleeve gastrectomy, food addiction is significantly improved. The weight change of patients with food addiction is less than that of patients without addiction 6 months after surgery.

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  • 收稿日期:2022-12-31
  • 最后修改日期:2023-06-25
  • 录用日期:2023-10-25
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