PET显像新技术在子宫恶性肿瘤中的进展
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南京医科大学第一附属医院

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江苏省医学重点人才基金项目


Progress of new PET imaging techniques in uterine malignancies
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Department of Nuclear Medicine, The First Affiliated Hospital of Nanjing Medical University University, Nanjing Jiangsu,

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Jiangsu Province Medical Key Talent Fund Project

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    摘要:

    摘要:子宫恶性肿瘤主要包括宫颈癌与子宫内膜癌,分别位列中国女性恶性肿瘤发病率的第二、第三位,其死亡率逐年递增,发病人群也趋于年轻化。为实现个体化精准治疗需对子宫病灶进行准确的分期和疗效评估。子宫恶性肿瘤PET显像(包括葡萄糖代谢、细胞增殖、雌激素受体、生长抑素受体、肿瘤乏氧和FAPIs显像等)在肿瘤分期、监测靶向治疗反应及早期识别放化疗耐药等方面具有显著优势,已成为宫颈癌及子宫内膜癌诊疗研究的热点方向。

    Abstract:

    Abstract: Uterine malignant tumors mainly include cervical cancer and endometrial cancer, which are the second and third most common female malignant tumors in China, respectively. The mortality of uterine malignant tumors is increasing by years, and the patients tend to be younger. In order to achieve individualized and accurate treatment, accurate staging of uterine lesions and high-quality therapeutic evaluation are needed. PET imaging of uterine malignant tumors, including glucose metabolism, cell proliferation, estrogen receptor, somatostatin receptor, hypoxia imaging and FAPIs imaging, has significant advantages in tumor staging, monitoring response to targeted therapy, and early identification of chemoradiotherapy resistance.

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  • 收稿日期:2023-05-17
  • 最后修改日期:2023-06-11
  • 录用日期:2023-08-29
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