肺肉瘤样癌免疫治疗新进展
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南京医科大学第一附属医院呼吸与危重症医学科

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国家自然科学基金项目(面上项目)


New Advances in Immunotherapy for Pulmonary Sarcomatoid Carcinoma
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1.Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Nanjing Medical University;2.Huang Mao

Fund Project:

The National Natural Science Foundation of China (General Program)

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    摘要:

    肺肉瘤样癌(pulmonary sarcomatoid carcinoma, PSC)是非小细胞肺癌的一种罕见类型,具有高度侵袭性和异质性,对传统放化疗不敏感,预后极差。免疫治疗作为肺癌治疗领域的里程碑式进展,为驱动基因阴性的肺肉瘤样癌患者提供治疗新方向,有望改善患者临床预后。基于此,本文对国内外有关肺肉瘤样癌免疫治疗最新研究进展进行综述。

    Abstract:

    Pulmonary sarcomatoid carcinoma is a rare type of non-small cell lung cancer, characterized by high invasiveness and heterogeneity. It is insensitive to traditional radiotherapy and chemotherapy, resulting in an extremely poor prognosis. Immunotherapy, as a significant advancement in the field of lung cancer treatment, provides a new direction for patients with driver gene-negative pulmonary sarcomatoid carcinoma and holds promise for improving clinical outcomes. Based on this, this article reviews the latest research progress on the immunotherapy of pulmonary sarcomatoid carcinoma at home and abroad.

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  • 收稿日期:2024-01-09
  • 最后修改日期:2024-03-25
  • 录用日期:2024-04-10
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