Objective：This study aims to develop a biodegradable esophageal stent based on polycaprolactone (PCL) and poly(lactic-co-glycolic acid) (PLGA) blend materials. By adjusting the PLGA ratio (0%-35%), the study seeks to balance degradation rate and mechanical properties while exploring its in vitro degradation characteristics. Methods：Eight different stent formulations were prepared using Extrusion-based High-temperature Melt Rotary 3D Printing technology, combined with a honeycomb porous structure design (porosity 60%-70%). In vitro degradation experiments were conducted over 8 weeks using artificial saliva (pH ≈ 6.6) and artificial gastric juice (pH ≈ 4.0). Results：The results demonstrated that the PLGA ratio significantly affected the degradation rate, with higher PLGA content accelerating the degradation of the stent (weight loss increased from 5.3% to 42.7%). Additionally, the blend of PLGA and PCL exhibited a synergistic effect, leading to stage-wise disintegration phenomena (when PLGA content was ≥25%). Conclusion：By adjusting the PLGA ratio, a degradation cycle ranging from 4 to 24 weeks was achieved, meeting the diverse clinical needs from congenital stricture to acute inflammation. Furthermore, the combination of 3D printing technology with biomimetic morphology and porous structure design significantly improved the tissue conformity and anti-displacement properties of the stent. These findings provide a theoretical basis and technical support for personalized treatment with biodegradable esophageal stents.