同种肝细胞移植排斥机理的初步探讨
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

基金项目:


reliminary Investigation of the Rejection Mechanisms in Allogeneic Hepatocyte Transplantation
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的 通过检测系统性红斑狼疮(SLE)患者血清白细胞介素-1、-6、-8(IL-1、-6、-8)可溶性白细胞介素-2受体(SIL-2R)水平,探讨细胞因子和SLE活动性的关系。方法 选择46例活动性SLE患者,并将其分成轻,中,重三组及狼疮肾(LN)和非LN两类,采用ELISA法测定其血清IL-1,SIL-2R,IL-8水平。结果 SLE患者血清IL-1,SIL-2R,IL-8水平显著高于正常对照

    Abstract:

    Objective To confirm the existence of allogeneic hepatocyte transplantation and investigate its mechanisms. Methods The hepatic failure rats induced by D-galatosamine were transplanted with allogeneic hepatocytes into their spleens. The spleen specimens obtained at different time after transplantation were examined by immunohistochemistry. Results CD+4, CD+\-8a lymphocytes and IgM antibodies were found in the rat spleen at 12 h post-graft and IgG antibodies at 24 h post-graft. They existed for one week after transplantation. Conclusion Both humoral and cellular immune respone participate in the rejection of allogeneic hepatocyte transplantation.

    参考文献
    相似文献
    引证文献
引用本文

张道珍,邢树忠,武和明,李宏卫,武正炎,范萍,俞悦,赵中辛,丁友成.同种肝细胞移植排斥机理的初步探讨[J].南京医科大学学报(自然科学版),2000,20(01):

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期:
  • 出版日期:
通知关闭
郑重声明