Objective： To investigate the change of TDI parameters after right ventricular pacing， and to reveal the effects of VVI and DDD on myocardial contractile function. Methods：The study included 3 groups， VVI group（30 patients receiving single-chamber pacing）， DDD group（32 patients receiving dual-chamber pacing），control group（32 healthy human）. TDI parameters of regional myocardium were observed. Results：PSV， PSS and PSSR were lowest in VVI group， followed by DDD group and control group. The number of the segments with significantly decreased PSSR was less than that of the segments with decreased PSV and PSR. In the two pacing groups， PSVT， PSST and PSSRT of left ventricle prolonged significantly， but those of right ventricle were shortened. Conclusion：TDI is a noninvasive method to evaluate the regional myocardium contraction after recent pacing. After pacing， there is no significant change in strain rate， and the decrease of velocity and strain are most in left ventricle. It is suggested that there is no significant change of the left ventricular contraction after pacing， but the contraction of the right ventricle in VVI mode is decreased compared with DDD mode.