Objective:To develop a new kind of abdominal transfered colon carcinoma model in rats, and to evaluate the healing of stoma by measure the concentrations of hydroxyproline in tissue of colon stoma. Methods:Colon Carcinoma cell SW480 was inoculated subcutaneously into athymic mice to develop an implantation tumor,Subsequently the tumor lumps were implanted to the SD rats’ colon mucosa to setup the model. The tumor tissues were cut and the colons were anastomosed. 6 rats which were not implanted tumors but colons been cut and anastomosed were included into control group. Then measure the tensile strength and concentrations of hydroxyproline of colon stoma tissue with HPLC. Results:60% rats were success to establish abdominal transfered Colon Carcinoma models. The tensile strength and the concentrations of hydroxyproline in colon stoma tissue were both lower in experiment group than in control group(P<0.05.) Conclusion:It’s a reliable method to build tumor model and tumor significantly delays the healing of stoma.