Abstract:Objective:To investigate the correlations between electrogastrogram(EGG) and gastric emptying(GE) in patients with functional dyspepsia(FD). Methods:Fifty-one patients with FD were detected by polygraph ID 4-channel EGG analysis system(EGG) and solid radiopaque marker 5h after a solid meal(GE). Results:31.4% patients with FD showed delayed GE, 72.6% showed abnormal EGG. There were no significant differences between normal EGG groups and abnormal EGG groups in average percentage of postprandial 5 h emptying. In patients who had both abnormal EGG and delayed GE, EGG abnormility mainly exhibited dysrhythmia, and the dominant frequency of EGG were normal. Some patients also exhibited non-enhancive dominant power postprandial. There were no significant differences among patients with mild, moderate and severe symptoms in GE percentage. The patients with severe symptoms had higher dysrhythmia percentage than those in mild and moderate symptoms(P < 0.05), but there was no significant difference between the patients with mild and moderate symptoms. There were no significant difference of GE percentage between Hp negative groups and Hp positive groups, but the dysrhymia percentage of Hp positive groups was higher than Hp negative groups(P < 0.05). There were also no significant differences between active gastritis group and inactive gastris group in both dysrhymia percentage and GE percentage. Conclusion:The abnormality of EGG plays an important role in the pathogenesis of FD. There was no significant relationship between EGG and GE. The patients with severe symptoms and with Hp positive have higher abnormal EGG percentage. Whether the gastritis is active or not, that was no significant correlation with EGG or GE percentage.