超声造影在肝脏恶性肿瘤射频或微波治疗后近期疗效应用评价
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南京医科大学创新基金(CX2003017)


To evaluate the immediate curative effect of liver cancer percutaneous microwave therapy or radio frequency ablation using contrast-enhanced ultrasound
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    摘要:

    目的:通过对肝脏恶性肿瘤靶区局部射频或微波治疗前后超声造影的观察,探讨超声造影方法评估局部治疗近期疗效的可行性。方法:56个(病灶)肝脏恶性肿瘤患者均经增强CT或超声造影、活检证实,局部治疗疗程结束后行超声造影观察局部治疗区域,以治疗后治疗区造影各时相无造影增强,血清学指标正常作为局部治疗彻底的标准,动脉期治疗区残存增强病灶,门脉期及延迟期病灶造影清退,类似于治疗前造影特点为治疗不彻底,作为下次治疗的靶目标区,直至达到彻底治疗标准。结果:超声造影可以动态显示局部治疗区域的微循环特点及残存病灶的各种形态。结论:超声造影可以显示出局部治疗的治疗区域形态以及残存肿瘤表现,并确定将此作为靶治疗区域,为再次补充治疗提供导向作用。

    Abstract:

    Objective:To evaluate the efficacy of CEUS(contrast enhanced ultrasonography) in accessing immediate curative effects of malignant liver tumor after radiofrequency or microwave therapy. Methods:Fifty-six lesions confirmed by contrast CT, CEUS or biopsy were observed. No enhancement through all periods and normalized serologic indexes were considered as the standard of complete treatment. The phenomena such as residual lesions enhanced through the arterial period, diminished through venous and delayed phase, which similar to that before therapy, was considered as standard of incomplete treatment. Consecutive therapy was applied to those regions until that reached complete treatment standard. Results:CEUS can dynamically show the microcirculation characteristics of therapy regions and different appearance of residual lesions. Conclusion:CEUS can show appearances of therapy regions as well as residual lesions,which should help to make supplementary therapeutic plans.

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胡建群,叶新华,范伯强,林红军,汪惠宁,彭小静,苗 毅,郭 峰,范钦和,俞同福,张伟民.超声造影在肝脏恶性肿瘤射频或微波治疗后近期疗效应用评价[J].南京医科大学学报(自然科学版),2007,(11):1290-1293

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  • 收稿日期:2007-07-17
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