Objective:To investigate the relationship between microalbuminuria and arterial stiffness index in diabetes patients. Methods:A total of 135 patients with diabetes were studied. Arterial Stiffness Index(ASI) which can reflect large arterial compliance was measured by CardioVisionMS-2000 arterial stiffness detector. Albumin/creatinine ratio(ACR) was determined. Results:ASI was higher in high ACR group than in normal ACR group. There were significant differences in age,SBP,PP,HDL-C,GFR,HbA1C,duration of diabetes between two groups(P < 0.05). There was a positive correlation between age,SBP,PP,LDL-C,ACR,HbA1C,duration of diabetes and ASI showed by single factor correlation analysis methods(P < 0.05) However there was a negative correlation between GFR and ASI(P < 0.05). PP,ACR,HbA1C,duration of diabetes were independent risk factors of ASI showed by multiple linear stepwise regression analysis method. Conclusion:The artery compliance as measured by ASI is increased in patients with type 2 diabetes and raised ACR.