番茄红素对SD老龄大鼠抗氧化作用的影响
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Effect of lycopene on antioxidation in SD old rats
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    目的:探讨番茄红素对SD老龄大鼠抗氧化作用的影响-方法:48只SD老龄大鼠以初始血清中丙二醛(MDA)的含量随机分成3个实验组和1个对照组-各组大鼠分别经口灌胃给予0.066 4 g/(kg·天)-0.134 0g/(kg·天)-0.400 0 g/(kg·天)的番茄红素及食用油30天后,测定血清中MDA含量-超氧化物歧化酶(SOD)活力-谷胱甘肽过氧化物酶(GSH-Px)活力-肝组织中脂褐质含量-结果:0.4 g/(kg·天)组大鼠血清中MDA含量显著低于对照组, 0.134 g/(kg·天)-0.400 g/(kg·天)组大鼠血清中SOD活力显著高于对照组-结论:番茄红素对SD老龄大鼠具有抗氧化作用-

    Abstract:

    Objective:To study the effects of the lycopene on antioxidation in SD old rats. Methods:According to the initial contents of malondiadehycle(MDA) in the serum, 48 SD old rats were devided radomly to 4 groups. After the rats were orally administered with 0.066 4 g/(kg·d), 0.134 g/(kg·d), 0.4 g/(kg·d) lycopene and the oil for 30 days, the concents of serum MDA, the energy of serum SA, the energy of serum GSH-Px and the contents of lipofasciin in liver were observed. Results:Compared with the oil group, the concents of serum MDA were decreased significantly in 0.4 g/(kg·d) group, and the energy of serum SA was increased significantly in 0.134 g/(kg·d) and 0.4 g/(kg·d) groups. Conclusion:Lycopene has antioxidant effect on SD old rats.

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张成香,李世芬,赵 岩.番茄红素对SD老龄大鼠抗氧化作用的影响[J].南京医科大学学报(自然科学版),2008,28(7):899-901905

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  • 收稿日期:2008-03-07
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