丝裂霉素联合Ahmed减压阀植入术治疗难治性青光眼疗效好
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Observation on the long-term effect of mitomycin C combined with the Ahmed glaucoma valve implantation on the refractory glaucoma
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    目的:观察丝裂霉素(mitomycin C,MMC)联合Ahmed减压阀植入术治疗难治性青光眼的疗效-方法:应用Ahmed青光眼减压阀植入手术治疗32例35眼难治性青光眼,术后随访一年,观察其临床疗效及其手术并发症-结果:本组成功率为80.0%; 眼压由术前的(47.28 ± 13.14)mmHg 降至术后的(17. 62 ± 6. 42)mmHg-采用配对t检验差异有统计学意义(P < 0.01)-术后并发症为:引流盘周纤维包裹2眼(5.7%),浅前房2眼(5.7%),引流管口堵塞2眼(5.7%),脉络膜脱离1眼 (2.8%)-结论:应用丝裂霉素联合Ahmed减压阀植入手术治疗难治性青光眼是一种相对有效-安全的治疗方法-

    Abstract:

    Objective:To observe the long-term effect of mitomycin C combined with Ahmed glaucoma valve(AGV) implantation on the refractory glaucoma. Methods:After A GV implantation, a retrospective study of clinical effect and complications were conducted on 35 eyes from 32 patients with refractory glaucoma with one-year follow-up. Results:The long-term successful rate was 80.0%. The average IOP decreased from the preoperative(47.28 ± 13.14)mmHg to the postoperative(17.62 ± 6.42)mmHg. The complications caused by the unsuccessful operation included bleb encapsulation in 2 eyes(5.7%), flat anterior chamber in 2 eyes(5.7%), tube blockage in 2 eyes(5.7%), and exudativech roidal detachment in 1 eye(2.8%). Conclusion:Mitomycin C combined with the AGV implantation surgery may be effective and safe for treating refractory glaucoma.

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徐晓红,袁志兰,于 焱,计江东.丝裂霉素联合Ahmed减压阀植入术治疗难治性青光眼疗效好[J].南京医科大学学报(自然科学版),2009,29(2):260-263

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  • 收稿日期:2008-04-17
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