Objective:To investigate the clinical efficacy of Bisoprolol on the diastolic heart failure in the elderly hypertensive patients. Methods:Eishty-three elderly hypertensive patients with diastolic heart failure were studied. The treated group(n = 42) recieved Bisoprolol and common anti-hypertensive and anti-heart-failure drugs,while the control group(n = 41)were treated with the common drugs alone. Then were compared after treatments in the treated group and in the control group. Results:In the treatment group total effectiveness is 95%,while in the control group the total effectiveness is 80%. There is significant difference between the two groups. (P < 0.05).All data after treatments in the treated group such as isovolumic relaxation time(IVRT),early left ventricular filling velocity(E),velocity of left ventricular filling contributed by atrial contraction(A),E/A,E-wave deceleration time(DT),left atrial diameter(LAD),systolic blood pressure,diastolic biood pressure and heart rate(HR)were better than those before treatments(P < 0.01). The treatment group improved more signiticanthj than the control group(P < 0.01,P < 0.05). Conclusion:The Bisoprolol could Greduce blood pressure,heart rate obviously and improve the heart diastolic function.