Objective: To evaluate the long-term outcomes and safety of laser in situ keratomilesis (LASIK) for myopia. Methods: 39 cases (77 eyes), who underwent LASIK, were divided into two groups: myopia ≤-6.0 D and >-6.0 D . All patients were followed-up for 10 years after surgery. The main parameters for evaulation were predictability, stability, safety and efficacy. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), refractions, topography, corneal thickness and postoperative complications were recorded at 10 years. Results: At the 10th year, 63% of eyes with myopia ≤-6.0 D and 42% of eyes with myopia>-6.0 D had 1.0 or better UCVA, 27% of eyes with myopia ≤-6.0 D and 58% of eyes with myopia>-6.0 D had less than 1.0 UCVA . 98% of eyes with myopia ≤-6.0 D and 72% of eyes with myopia>-6.0 D had 1.0 or better BCVA(P < 0.05). There were significant differences at values of Diff value on anterior and posterior surface,Irreg at 3 mm and 5 mm zone obtained from Orbscan Ⅱand corneal thickness between pre- and post- operation(P < 0.01). Mean corneal thickness at the 10th year postoperatively was higher than attempted residual corneal thickness after ablation, it suggested that the stroma of cornea proliferated. Conclusion:LASIK surgery is safe and has predictable and stable results in refractive and visual outcomes in correcting myopia on long-term follow-up.