双源CT冠状动脉CTA不良反应的分析与处理
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Analysis and solutions of adverse reaction in dual-source CT coronary arteriography
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    目的: 分析双源CT冠状动脉CTA检查过程中出现的各种不良反应的发生原因与处理-方法:收集2010年1月1日至2010年5月18日间1 405名接受冠状动脉CTA病例,结合过敏史及检查前的处理,分析不良反应的发生率以及相应的处理-结果:检查者中既往有药物过敏史或过敏性疾病患者79人,发生不同程度不良反应者18人;无过敏史者1326人,出现不良反应者35人(P < 0.01)-有过敏史受检者42位检查前接受地塞米松处理,37位未接受地塞米松处理,均有9人发生不同程度不良反应(P > 0.05),但未接受地塞米松处理的患者中有2例发生过敏性休克-53例发生不良反应受检者经处理均好转-结论:双源CT冠状动脉CTA发生不良反应时,应根据不同程度采取方法及时处理,受检者有无药物过敏史等高危因素与冠状动脉CTA不良反应的发生有明显相关,检查前用地塞米松预处理不能明显降低冠状动脉CTA不良反应的发生,但可能减轻不良反应的程度-

    Abstract:

    Objective: To analyze the incidence rate and and management of adverse reaction in dual-source CT coronary arteriography(DSCT-CCTA). Methods: Total 1405 patients who received DSCT coronary angiography examination were enrolled in this study from Jan 1, 2010 to May 18, 2010. Considering both the allergic history and the pre-examination management, the incidence rate and the medical managements of adverse reaction were recorded and analyzed. Results: There were 79 patients who had a history of drug allergy or other allergic diseases. Adverse reaction occurred in 18 patients of those patients. The other 1 326 patients had no history of allergic disease, and adverse reaction occurred in 35 patients (P < 0.01). Among those patients of allergic history, 42 cases received pre-examination treatment of Dexamethasone. There was no significant difference of the incidence rate of adverse reaction between those patients with or without pre-examination treatment (P > 0.05). However, allergic shock occurred in two patients without pre-examination treatment of Dexamethasone. Those 53 patients with adverse reaction recovered after proper medical treatment. Conclusion:When adverse reaction occurs during the DSCT-CCTA, patients should be treated individually according to the degree of adverse reaction. Adverse reaction was highly correlated to allergic history. Pre-examination treatment of Dexamethasone could not reduce the incidence rate of adverse reaction significantly, but may relieve the degree of adverse reaction.

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李 梅,唐立钧,马胜华,陈 静,陈大红.双源CT冠状动脉CTA不良反应的分析与处理[J].南京医科大学学报(自然科学版),2011,(1):112-114

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  • 收稿日期:2010-07-21
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