Objective: To compare the clinical results of dilator-kyphoplasty(DKP),balloon-kyphoplasty(BKP) and Sky-bone expander kyphoplasty(EKP). Methods:A retrospective study was done from October 2006 to February 2010, and 71 cases(71 vertebra) with DKP, 55 cases (55 vertebra) with BKP and 22 cases (22 vertebra) with EKP procedures were performed. The operating time, bleeding volume, cement injecting volume of cement were recorded during operation. The patients′ VAS score and ODI score were evaluated after operation. The distribution of the cement and the restoration of vertebral height and Cobb angle were observed post-operation. Results:There are no significant differences in operative time and bleeding volume of every vertebrae in these three groups. The EKP group had smaller cement injected volume than other groups. The VAS and ODI scores were decreased significantly, and the vertebral height and Cobb angle were restored in three groups after operation. The post-operative changes were significantly more pronounced in the DKP group. Conclusion:DKP, BKP and EKP were all effective and safe in the treatment of osteoporosis vertebral compression fractures. The vertebral height and Cobb angle were restored in three groups. The post-operative changes were more pronounced in the DKP group. There is lower cement leakage rate in DKP than the other two methods, because the bone cement was injected in dough state and the vertebral body was parallelly strutted.